蜂鸟电竞在线入口 Test Guidelines for Chemicals


What's new

On 30 June 2022, the 蜂鸟电竞在线入口 published 6 new Test Guidelines and 10 updated or corrected Test Guidelines.


The following Test Guidelines were updated or corrected and published on 30 June 2022. A special highlight for Test Guideline 442E that integrates the GARDSkin assay: the method covers a genomic expression of a defined set of genes predicting skin sensitisation potential of test chemicals. This is the first harmonised method that generates and interprets genomic data for a regulatory endpoint.





蜂鸟电竞在线入口 Test Guidelines 

‌The 蜂鸟电竞在线入口 Guidelines for the Testing of Chemicals   are a unique tool for assessing the potential effects of chemicals on human health and the environment. A ccepted internationally as standard methods for safety testing, the Guidelines are used by professionals in industry, academia and government involved in the testing and assessment of chemicals (industrial chemicals, pesticides, personal care products, etc.). These Guidelines are continuously expanded and updated to ensure they reflect the state-of-the-art science and techniques to meet member countries regulatory needs. The Guidelines are elaborated with the assistance of experts from regulatory agencies, academia, industry, environmental and animal welfare organisations. 

蜂鸟电竞在线入口 Test Guidelines are covered by the 蜂鸟电竞在线入口 Mutual Acceptance of Data (MAD) system . Under this system, laboratory test results related to the safety of chemicals that are generated in accordance with  蜂鸟电竞在线入口 Test Guidelines  and  蜂鸟电竞在线入口 Principles of Good Laboratory Practices   are accepted in all 蜂鸟电竞在线入口 countries and adherent countries for the purpose of safety assessment and other uses relating to the protection of human health and the environment.


The 蜂鸟电竞在线入口 Guidelines for the Testing of Chemicals   are split into five sections:

The full list of adopted Test Guidelines, the draft TGs under public commenting rounds, the draft Guidance and review documents are available on the  Test Guidelines Programme


Publications in the Series of Testing and Assessment

This  Series  includes publications related to testing and assessment of chemicals; some of them support the development of 蜂鸟电竞在线入口 Test Guidelines (e.g. validation reports, guidance documents, detailed review papers).

Find out more about our work 

Find out about our areas of work, upcoming webinars, programme of work and the Council Acts related to Test Guidelines.  


Test Guidelines that have been deleted or replaced by updated versions

The Test Guidelines that have been deleted should not be used for new testing. They are included here because it may be useful to consult them in the framework of the assessment of substances based on old study reports. The guaranties of Mutual Acceptance of Data (MAD) would not apply if these Test Guidelines were used for new testing.

In November 2012, the Joint Meeting of the Chemicals Committee and Working Party on Chemicals, Pesticides and Biotechnology decided on a transition period of 18 months, between the Council Decision and the effective deletion, for Test Guidelines that have been updated or deleted. For more information, please read the  presentation: Update of Test Guidelines and the Mutual Acceptance of Data .


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